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KMID : 0616120120430020101
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Korean Journal of Pharmacognosy
2012 Volume.43 No. 2 p.101 ~ p.106
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Anti-hyperlipidemic Effect of the Isolated Component, Quercetin-3-O-rhamnoside and the Fractions from the Extract of Houttuynia Cordata in Mice
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Kim Do-Kuk
Kim Se-Gun
Amrit Poudel
Jeong Tae-Suk
Jung Hyun-Ju
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Abstract
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The anti-hyperlipidemic effect of Houttuynia cordata was assessed in poloxamer-407 induced hyperlipidemic mice model. The butanol fraction and its isolated compound, quercetin-3-O-rhamnoside, significantly reduced the blood triglyceride and total-cholesterol level and increased the blood HDL-cholesterol level. They also showed the significant reductive effect on the blood AST and ALT level, rising in proportion to the liver damage, in hyperlipidemic mice.
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KEYWORD
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Houttuynia cordata, Saururaceae, Quercetin-3-O-rhamnoside, Anti-hyperlipidemic effect
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